Which of the following is true about the development and spread of multidrug-resistant organisms (MDROs) in nursing homes?

Colonization pressure is a significant factor in the transmission of multidrug-resistant organisms (MDROs) within nursing homes. This concept refers to the presence of a high number of individuals carrying MDROs, which increases the likelihood of spread to others, especially in environments where residents may be vulnerable due to compromised health. When colonization pressure is high, even a small breach in infection control measures can lead to an outbreak, as the environment becomes saturated with these resistant organisms.

In the context of nursing homes, where residents often share space and may have weakened immune systems, understanding and controlling colonization pressure is crucial to preventing the spread of MDROs. Effective strategies might include monitoring antibiotic use, implementing strict infection control measures, and ensuring that carriers are managed appropriately to reduce the risk of transmission.

The other options suggest misconceptions about infection control and the factors contributing to MDRO development. For instance, effective isolation practices are essential in controlling infections; improper or lack of hand hygiene significantly impacts transmission rates, and antibiotic use is well-documented to play a major role in developing resistance among bacteria. Therefore, recognizing colonization pressure as a contributor to MDRO transmission is essential for implementing effective infection prevention strategies in nursing homes.